Human SERPINB1 activation kit by CRISPRa

CAT#: GA101378

SERPINB1 CRISPRa kit - CRISPR gene activation of human serpin family B member 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SERPINB1
• Locus ID: 1992
• Kit Components:

  GA101378G1, SERPINB1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101378G2, SERPINB1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101378G3, SERPINB1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_030666, NR_073111, NR_073112
• Synonyms: EI; ELANH2; HEL-S-27; HEL57; LEI; M/NEI; MNEI; PI-2; PI2
• Summary: 'The protein encoded by this gene is a member of the serpin family of proteinase inhibitors. Members of this family maintain homeostasis by neutralizing overexpressed proteinase activity through their function as suicide substrates. This protein inhibits the neutrophil-derived proteinases neutrophil elastase, cathepsin G, and proteinase-3 and thus protects tissues from damage at inflammatory sites. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]'