Human Eph receptor A7 (EPHA7) activation kit by CRISPRa

CAT#: GA101424

EPHA7 CRISPRa kit - CRISPR gene activation of human EPH receptor A7

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EPHA7
• Locus ID: 2045
• Kit Components:

  GA101424G1, Eph receptor A7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101424G2, Eph receptor A7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101424G3, Eph receptor A7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001288629, NM_001288630, NM_004440
• Synonyms: EHK-3; EHK3; EK11; HEK11
• Summary: 'This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Increased expression of this gene is associated with multiple forms of carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]'