Human EFEMP1 activation kit by CRISPRa

CAT#: GA101540

EFEMP1 CRISPRa kit - CRISPR gene activation of human EGF containing fibulin extracellular matrix protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EFEMP1
• Locus ID: 2202
• Kit Components:

  GA101540G1, EFEMP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101540G2, EFEMP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101540G3, EFEMP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001039348, NM_001039349, NM_004105, NM_018894
• Synonyms: DHRD; DRAD; FBLN3; FBNL; FIBL-3; MLVT; MTLV; S1-5
• Summary: 'This gene encodes a member of the fibulin family of extracellular matrix glycoproteins. Like all members of this family, the encoded protein contains tandemly repeated epidermal growth factor-like repeats followed by a C-terminus fibulin-type domain. This gene is upregulated in malignant gliomas and may play a role in the aggressive nature of these tumors. Mutations in this gene are associated with Doyne honeycomb retinal dystrophy. Alternatively spliced transcript variants that encode the same protein have been described.[provided by RefSeq, Nov 2009]'