Human FCGRT activation kit by CRISPRa

CAT#: GA101553

FCGRT CRISPRa kit - CRISPR gene activation of human Fc fragment of IgG receptor and transporter

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FCGRT
• Locus ID: 2217
• Kit Components:

  GA101553G1, FCGRT gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101553G2, FCGRT gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101553G3, FCGRT gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001136019, NM_004107
• Synonyms: alpha-chain; FCRN
• Summary: 'This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]'