Human FKBP2 activation kit by CRISPRa

CAT#: GA101599

FKBP2 CRISPRa kit - CRISPR gene activation of human FKBP prolyl isomerase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FKBP2
• Locus ID: 2286
• Kit Components:

  GA101599G1, FKBP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101599G2, FKBP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101599G3, FKBP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001135208, NM_004470, NM_057092, NM_001370363, NM_001370360, NM_001370362, NM_001370365, NM_001370367
• Synonyms: FKBP-13; PPIase
• Summary: 'The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008]'