Human OPN1MW activation kit by CRISPRa

CAT#: GA101771

OPN1MW CRISPRa kit - CRISPR gene activation of human opsin 1, medium wave sensitive

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: OPN1MW
• Locus ID: 2652
• Kit Components:

  GA101771G1, OPN1MW gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101771G2, OPN1MW gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101771G3, OPN1MW gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000513
• Synonyms: CBBM; CBD; COD5; GCP; GOP; OPN1MW1
• Summary: 'This gene encodes for a light absorbing visual pigment of the opsin gene family. The encoded protein is called green cone photopigment or medium-wavelength sensitive opsin. Opsins are G-protein coupled receptors with seven transmembrane domains, an N-terminal extracellular domain, and a C-terminal cytoplasmic domain. The long-wavelength opsin gene and multiple copies of the medium-wavelength opsin gene are tandemly arrayed on the X chromosome and frequent unequal recombination and gene conversion may occur between these sequences. X chromosomes may have fusions of the medium- and long-wavelength opsin genes or may have more than one copy of these genes. Defects in this gene are the cause of deutanopic colorblindness. [provided by RefSeq, Mar 2009]'