Human GHRHR activation kit by CRISPRa

CAT#: GA101798

GHRHR CRISPRa kit - CRISPR gene activation of human growth hormone releasing hormone receptor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GHRHR
• Locus ID: 2692
• Kit Components:

  GA101798G1, GHRHR gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101798G2, GHRHR gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101798G3, GHRHR gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000823, NM_001009824
• Synonyms: GHRFR; GRFR; IGHD1B
• Summary: 'This gene encodes a receptor for growth hormone-releasing hormone. Binding of this hormone to the receptor leads to synthesis and release of growth hormone. Mutations in this gene have been associated with isolated growth hormone deficiency (IGHD), also known as Dwarfism of Sindh, a disorder characterized by short stature. [provided by RefSeq, Jun 2010]'