Human GNAL activation kit by CRISPRa

CAT#: GA101847

GNAL CRISPRa kit - CRISPR gene activation of human G protein subunit alpha L

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GNAL
• Locus ID: 2774
• Kit Components:

  GA101847G1, GNAL gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101847G2, GNAL gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101847G3, GNAL gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001142339, NM_001261443, NM_001261444, NM_002071, NM_182978, NM_001369387
• Synonyms: DYT25
• Summary: 'This gene encodes a stimulatory G protein alpha subunit which mediates odorant signaling in the olfactory epithelium. This protein couples dopamine type 1 receptors and adenosine A2A receptors and is widely expressed in the central nervous system. Mutations in this gene have been associated with dystonia 25 and this gene is located in a susceptibility region for bipolar disorder and schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]'