Human GNAQ activation kit by CRISPRa

CAT#: GA101849

GNAQ CRISPRa kit - CRISPR gene activation of human G protein subunit alpha q

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GNAQ
• Locus ID: 2776
• Kit Components:

  GA101849G1, GNAQ gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101849G2, GNAQ gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101849G3, GNAQ gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002072
• Synonyms: CMC1; G-ALPHA-q; GAQ; SWS
• Summary: 'This locus encodes a guanine nucleotide-binding protein. The encoded protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospolipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation. A related pseudogene exists on chromosome 2.[provided by RefSeq, Nov 2010]'