Human GPD2 activation kit by CRISPRa

CAT#: GA101885

GPD2 CRISPRa kit - CRISPR gene activation of human glycerol-3-phosphate dehydrogenase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GPD2
• Locus ID: 2820
• Kit Components:

  GA101885G1, GPD2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101885G2, GPD2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101885G3, GPD2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000408, NM_001083112
• Synonyms: GDH2; GPDM; mGPDH
• Summary: 'The protein encoded by this gene localizes to the inner mitochondrial membrane and catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate, using FAD as a cofactor. Along with GDP1, the encoded protein constitutes the glycerol phosphate shuttle, which reoxidizes NADH formed during glycolysis. Two transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Jan 2010]'