Human Granzyme A (GZMA) activation kit by CRISPRa

CAT#: GA102039

GZMA CRISPRa kit - CRISPR gene activation of human granzyme A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GZMA
• Locus ID: 3001
• Kit Components:

  GA102039G1, Granzyme A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102039G2, Granzyme A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102039G3, Granzyme A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006144
• Synonyms: CTLA3; HFSP
• Summary: 'Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells. [provided by RefSeq, Jul 2008]'