Human hnRNP U (HNRNPU) activation kit by CRISPRa

CAT#: GA102180

HNRNPU CRISPRa kit - CRISPR gene activation of human heterogeneous nuclear ribonucleoprotein U

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HNRNPU
• Locus ID: 3192
• Kit Components:

  GA102180G1, hnRNP U gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102180G2, hnRNP U gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102180G3, hnRNP U gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004501, NM_031844
• Synonyms: hnRNP U; HNRNPU-AS1; HNRPU; SAF-A; SAFA; U21.1
• Summary: 'This gene encodes a member of a family of proteins that bind nucleic acids and function in the formation of ribonucleoprotein complexes in the nucleus with heterogeneous nuclear RNA (hnRNA). The encoded protein has affinity for both RNA and DNA, and binds scaffold-attached region (SAR) DNA. Mutations in this gene have been associated with epileptic encephalopathy, early infantile, 54. A pseudogene of this gene has been identified on chromosome 14. [provided by RefSeq, Jun 2017]'