Human TLX2 activation kit by CRISPRa

CAT#: GA102182

TLX2 CRISPRa kit - CRISPR gene activation of human T cell leukemia homeobox 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TLX2
• Locus ID: 3196
• Kit Components:

  GA102182G1, TLX2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102182G2, TLX2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102182G3, TLX2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001534, NM_016170
• Synonyms: Enx; HOX11L1; NCX
• Summary: 'This gene is a member of an orphan homeobox-containing transcription factor family. Studies of the mouse ortholog have shown that the encoded protein is crucial for the development of the enteric nervous system; in humans, loss-of-function may play a role in tumorigenesis of gastrointestinal stromal tumors. [provided by RefSeq, May 2010]'