Human ICAM2 activation kit by CRISPRa

CAT#: GA102300

ICAM2 CRISPRa kit - CRISPR gene activation of human intercellular adhesion molecule 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ICAM2
• Locus ID: 3384
• Kit Components:

  GA102300G1, ICAM2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102300G2, ICAM2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102300G3, ICAM2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000873, NM_001099786, NM_001099787, NM_001099788, NM_001099789
• Synonyms: CD102
• Summary: 'The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]'