Human IRF2 activation kit by CRISPRa

CAT#: GA102453

IRF2 CRISPRa kit - CRISPR gene activation of human interferon regulatory factor 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IRF2
• Locus ID: 3660
• Kit Components:

  GA102453G1, IRF2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102453G2, IRF2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102453G3, IRF2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002199
• Synonyms: IRF-2
• Summary: 'IRF2 encodes interferon regulatory factor 2, a member of the interferon regulatory transcription factor (IRF) family. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. However, IRF2 also functions as a transcriptional activator of histone H4. [provided by RefSeq, Jul 2008]'