Human KCNH2 activation kit by CRISPRa

CAT#: GA102533

KCNH2 CRISPRa kit - CRISPR gene activation of human potassium voltage-gated channel subfamily H member 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KCNH2
• Locus ID: 3757
• Kit Components:

  GA102533G1, KCNH2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102533G2, KCNH2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102533G3, KCNH2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000238, NM_001204798, NM_172056, NM_172057
• Synonyms: ERG-1; ERG1; H-ERG; HERG; HERG1; Kv11.1; LQT2; SQT1
• Summary: 'This gene encodes a voltage-activated potassium channel belonging to the eag family. It shares sequence similarity with the Drosophila ether-a-go-go (eag) gene. Mutations in this gene can cause long QT syndrome type 2 (LQT2). Transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]'