Human KCNJ9 activation kit by CRISPRa

CAT#: GA102541

KCNJ9 CRISPRa kit - CRISPR gene activation of human potassium voltage-gated channel subfamily J member 9

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KCNJ9
• Locus ID: 3765
• Kit Components:

  GA102541G1, KCNJ9 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102541G2, KCNJ9 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102541G3, KCNJ9 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004983
• Synonyms: GIRK3; KIR3.3
• Summary: 'Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. It associates with another G-protein-activated potassium channel to form a heteromultimeric pore-forming complex. [provided by RefSeq, Jul 2008]'