Human KEL activation kit by CRISPRa

CAT#: GA102565

KEL CRISPRa kit - CRISPR gene activation of human Kell metallo-endopeptidase (Kell blood group)

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KEL
• Locus ID: 3792
• Kit Components:

  GA102565G1, KEL gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102565G2, KEL gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102565G3, KEL gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000420
• Synonyms: CD238; ECE3
• Summary: 'This gene encodes a type II transmembrane glycoprotein that is the highly polymorphic Kell blood group antigen. The Kell glycoprotein links via a single disulfide bond to the XK membrane protein that carries the Kx antigen. The encoded protein contains sequence and structural similarity to members of the neprilysin (M13) family of zinc endopeptidases. [provided by RefSeq, Jul 2008]'