Human LASP1 activation kit by CRISPRa

CAT#: GA102662

LASP1 CRISPRa kit - CRISPR gene activation of human LIM and SH3 protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: LASP1
• Locus ID: 3927
• Kit Components:

  GA102662G1, LASP1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA102662G2, LASP1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA102662G3, LASP1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001271608, NM_006148, NR_073384
• Synonyms: Lasp-1; MLN50
• Summary: This gene encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer. [provided by RefSeq, Oct 2012]