Human LIM2 activation kit by CRISPRa

CAT#: GA102697

LIM2 CRISPRa kit - CRISPR gene activation of human lens intrinsic membrane protein 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: LIM2
• Locus ID: 3982
• Kit Components:

  GA102697G1, LIM2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102697G2, LIM2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102697G3, LIM2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001161748, NM_030657
• Synonyms: CTRCT19; MP17; MP19
• Summary: 'This gene encodes an eye lens-specific protein found at the junctions of lens fiber cells, where it may contribute to cell junctional organization. It acts as a receptor for calmodulin, and may play an important role in both lens development and cataractogenesis. Mutations in this gene have been associated with cataract formation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]'