Human Lamin B1 (LMNB1) activation kit by CRISPRa

CAT#: GA102712

LMNB1 CRISPRa kit - CRISPR gene activation of human lamin B1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: LMNB1
• Locus ID: 4001
• Kit Components:

  GA102712G1, Lamin B1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102712G2, Lamin B1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102712G3, Lamin B1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001198557, NM_005573, NR_134488
• Synonyms: ADLD; LMN; LMN2; LMNB
• Summary: 'This gene encodes one of the two B-type lamin proteins and is a component of the nuclear lamina. A duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]'