Human MAS1 activation kit by CRISPRa

CAT#: GA102820

MAS1 CRISPRa kit - CRISPR gene activation of human MAS1 proto-oncogene, G protein-coupled receptor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MAS1
• Locus ID: 4142
• Kit Components:

  GA102820G1, MAS1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102820G2, MAS1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102820G3, MAS1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002377, NM_001366704
• Synonyms: MAS; MGRA
• Summary: 'This gene encodes a class I seven-transmembrane G-protein-coupled receptor. The encoded protein is a receptor for angiotensin-(1-7) and preferentially couples to the Gq protein, activating the phospholipase C signaling pathway. The encoded protein may play a role in multiple processes including hypotension, smooth muscle relaxation and cardioprotection by mediating the effects of angiotensin-(1-7). [provided by RefSeq, May 2012]'