Human Midkine (MDK) activation kit by CRISPRa

CAT#: GA102857

MDK CRISPRa kit - CRISPR gene activation of human midkine

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MDK
• Locus ID: 4192
• Kit Components:

  GA102857G1, Midkine gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102857G2, Midkine gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102857G3, Midkine gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001012333, NM_001012334, NM_001270550, NM_001270551, NM_001270552, NM_002391, NR_073039
• Synonyms: ARAP; MK; NEGF2
• Summary: 'This gene encodes a member of a small family of secreted growth factors that binds heparin and responds to retinoic acid. The encoded protein promotes cell growth, migration, and angiogenesis, in particular during tumorigenesis. This gene has been targeted as a therapeutic for a variety of different disorders. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2012]'