Human SCF (KITLG) activation kit by CRISPRa

CAT#: GA102899

KITLG CRISPRa kit - CRISPR gene activation of human KIT ligand

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KITLG
• Locus ID: 4254
• Kit Components:

  GA102899G1, SCF gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102899G2, SCF gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102899G3, SCF gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000899, NM_003994
• Synonyms: FPH2; FPHH; Kitl; KL-1; MGF; SCF; SF; SHEP7
• Summary: 'This gene encodes the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]'