Human Myelin oligodendrocyte glycoprotein (MOG) activation kit by CRISPRa

CAT#: GA102956

MOG CRISPRa kit - CRISPR gene activation of human myelin oligodendrocyte glycoprotein

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MOG
• Locus ID: 4340
• Kit Components:

  GA102956G1, Myelin oligodendrocyte glycoprotein gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102956G2, Myelin oligodendrocyte glycoprotein gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102956G3, Myelin oligodendrocyte glycoprotein gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001008228, NM_001008229, NM_001170417, NM_001170418, NM_002433, NM_206809, NM_206810, NM_206811, NM_206812, NM_206813, NM_206814, NM_001363610
• Synonyms: BTN6; BTNL11; MOGIG2; NRCLP7
• Summary: 'The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]'