Human CD200 activation kit by CRISPRa

CAT#: GA102959

CD200 CRISPRa kit - CRISPR gene activation of human CD200 molecule

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CD200
• Locus ID: 4345
• Kit Components:

  GA102959G1, CD200 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102959G2, CD200 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102959G3, CD200 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001004196, NM_001004197, NM_001318826, NM_001318828, NM_001318830, NM_005944, NM_001365851, NM_001365852, NM_001365853, NM_001365854, NR_158642, NM_001365855
• Synonyms: MOX1; MOX2; MRC; OX-2
• Summary: 'This gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types, including B cells, a subset of T cells, thymocytes, endothelial cells, and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]'