Human MSX1 activation kit by CRISPRa

CAT#: GA102992

MSX1 CRISPRa kit - CRISPR gene activation of human msh homeobox 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MSX1
• Locus ID: 4487
• Kit Components:

  GA102992G1, MSX1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102992G2, MSX1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102992G3, MSX1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002448
• Synonyms: ECTD3; HOX7; HYD1; STHAG1
• Summary: 'This gene encodes a member of the muscle segment homeobox gene family. The encoded protein functions as a transcriptional repressor during embryogenesis through interactions with components of the core transcription complex and other homeoproteins. It may also have roles in limb-pattern formation, craniofacial development, particularly odontogenesis, and tumor growth inhibition. Mutations in this gene, which was once known as homeobox 7, have been associated with nonsyndromic cleft lip with or without cleft palate 5, Witkop syndrome, Wolf-Hirschom syndrome, and autosomoal dominant hypodontia. [provided by RefSeq, Jul 2008]'