Human Methylmalonyl Coenzyme A mutase (MUT) activation kit by CRISPRa

CAT#: GA103041

MMUT CRISPRa kit - CRISPR gene activation of human methylmalonyl-CoA mutase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MMUT
• Locus ID: 4594
• Kit Components:

  GA103041G1, Methylmalonyl Coenzyme A mutase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103041G2, Methylmalonyl Coenzyme A mutase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103041G3, Methylmalonyl Coenzyme A mutase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000255
• Synonyms: MCM
• Summary: 'This gene encodes the mitochondrial enzyme methylmalonyl Coenzyme A mutase. In humans, the product of this gene is a vitamin B12-dependent enzyme which catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA, while in other species this enzyme may have different functions. Mutations in this gene may lead to various types of methylmalonic aciduria. [provided by RefSeq, Jul 2008]'