Human MYBPC2 activation kit by CRISPRa

CAT#: GA103052

MYBPC2 CRISPRa kit - CRISPR gene activation of human myosin binding protein C, fast type

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MYBPC2
• Locus ID: 4606
• Kit Components:

  GA103052G1, MYBPC2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103052G2, MYBPC2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103052G3, MYBPC2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004533
• Synonyms: MYBPC; MYBPCF
• Summary: 'This gene encodes a member of the myosin-binding protein C family. This family includes the fast-, slow- and cardiac-type isoforms, each of which is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. The protein encoded by this locus is referred to as the fast-type isoform. Mutations in the related but distinct genes encoding the slow-type and cardiac-type isoforms have been associated with distal arthrogryposis, type 1 and hypertrophic cardiomyopathy, respectively. [provided by RefSeq, Jul 2012]'