Human Myosin 1C (MYO1C) activation kit by CRISPRa

CAT#: GA103080

MYO1C CRISPRa kit - CRISPR gene activation of human myosin IC

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MYO1C
• Locus ID: 4641
• Kit Components:

  GA103080G1, Myosin 1C gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103080G2, Myosin 1C gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103080G3, Myosin 1C gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001080779, NM_001080950, NM_033375, NM_001363855
• Synonyms: MMI-beta; MMIb; myr2; NMI
• Summary: 'This gene encodes a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. The related gene myosin IE has been referred to as myosin IC in the literature, but it is a distinct locus on chromosome 19. [provided by RefSeq, Jul 2008]'