Human CEACAM6 activation kit by CRISPRa

CAT#: GA103111

CEACAM6 CRISPRa kit - CRISPR gene activation of human carcinoembryonic antigen related cell adhesion molecule 6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CEACAM6
• Locus ID: 4680
• Kit Components:

  GA103111G1, CEACAM6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103111G2, CEACAM6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103111G3, CEACAM6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002483
• Synonyms: CD66c; CEAL; NCA
• Summary: 'This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19. [provided by RefSeq, Apr 2014]'