Human Neogenin (NEO1) activation kit by CRISPRa

CAT#: GA103172

NEO1 CRISPRa kit - CRISPR gene activation of human neogenin 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NEO1
• Locus ID: 4756
• Kit Components:

  GA103172G1, Neogenin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103172G2, Neogenin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103172G3, Neogenin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001172623, NM_001172624, NM_002499
• Synonyms: IGDCC2; NGN; NTN1R2
• Summary: 'This gene encodes a cell surface protein that is a member of the immunoglobulin superfamily. The encoded protein consists of four N-terminal immunoglobulin-like domains, six fibronectin type III domains, a transmembrane domain and a C-terminal internal domain that shares homology with the tumor suppressor candidate gene DCC. This protein may be involved in cell growth and differentiation and in cell-cell adhesion. Defects in this gene are associated with cell proliferation in certain cancers. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]'