Human NOVA1 activation kit by CRISPRa

CAT#: GA103244

NOVA1 CRISPRa kit - CRISPR gene activation of human NOVA alternative splicing regulator 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NOVA1
• Locus ID: 4857
• Kit Components:

  GA103244G1, NOVA1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA103244G2, NOVA1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA103244G3, NOVA1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002515, NM_006489, NM_006491, NM_001366391, NM_001366392, NM_001366395, NM_001366396, NM_001366397, NM_001366398, NM_001366390, NM_001366393, NM_001366394
• Synonyms: Nova-1
• Summary: This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]