Human NPY1R activation kit by CRISPRa

CAT#: GA103263

NPY1R CRISPRa kit - CRISPR gene activation of human neuropeptide Y receptor Y1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NPY1R
• Locus ID: 4886
• Kit Components:

  GA103263G1, NPY1R gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103263G2, NPY1R gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103263G3, NPY1R gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000909
• Synonyms: NPY1-R; NPYR
• Summary: 'This gene belongs to the G-protein-coupled receptor superfamily. The encoded transmembrane protein mediates the function of neuropeptide Y (NPY), a neurotransmitter, and peptide YY (PYY), a gastrointestinal hormone. The encoded receptor undergoes fast agonist-induced internalization through clathrin-coated pits and is subsequently recycled back to the cell membrane. Activation of Y1 receptors may result in mobilization of intracellular calcium and inhibition of adenylate cyclase activity. [provided by RefSeq, Aug 2013]'