Human PDE4D activation kit by CRISPRa

CAT#: GA103441

PDE4D CRISPRa kit - CRISPR gene activation of human phosphodiesterase 4D

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PDE4D
• Locus ID: 5144
• Kit Components:

  GA103441G1, PDE4D gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103441G2, PDE4D gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103441G3, PDE4D gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001104631, NM_001165899, NM_001197218, NM_001197219, NM_001197220, NM_001197221, NM_001197222, NM_001197223, NM_006203, NM_001349241, NM_001349242, NM_001349243, NM_001364599, NM_001364600, NM_001364602, NM_001364601, NM_001364603, NM_001364604
• Synonyms: ACRDYS2; DPDE3; HSPDE4D; PDE4DN2; PDE43; STRK1
• Summary: 'This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.[provided by RefSeq, Sep 2009]'