Human Profilin 1 (PFN1) activation kit by CRISPRa

CAT#: GA103505

PFN1 CRISPRa kit - CRISPR gene activation of human profilin 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PFN1
• Locus ID: 5216
• Kit Components:

  GA103505G1, Profilin 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103505G2, Profilin 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103505G3, Profilin 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005022
• Synonyms: ALS18
• Summary: 'This gene encodes a member of the profilin family of small actin-binding proteins. The encoded protein plays an important role in actin dynamics by regulating actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome, and the encoded protein may also play a role in Huntington disease. Multiple pseudogenes of this gene are located on chromosome 1. [provided by RefSeq, Jul 2012]'