Human Alpha 2 Antiplasmin (SERPINF2) activation kit by CRISPRa

CAT#: GA103604

SERPINF2 CRISPRa kit - CRISPR gene activation of human serpin family F member 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SERPINF2
• Locus ID: 5345
• Kit Components:

  GA103604G1, Alpha 2 Antiplasmin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103604G2, Alpha 2 Antiplasmin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103604G3, Alpha 2 Antiplasmin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000934, NM_001165920, NM_001165921
• Synonyms: A2AP; AAP; ALPHA-2-PI; API; PLI
• Summary: 'This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]'