Human PODXL activation kit by CRISPRa

CAT#: GA103644

PODXL CRISPRa kit - CRISPR gene activation of human podocalyxin like

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PODXL
• Locus ID: 5420
• Kit Components:

  GA103644G1, PODXL gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103644G2, PODXL gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103644G3, PODXL gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001018111, NM_005397
• Synonyms: Gp200; PC; PCLP; PCLP-1
• Summary: 'This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin. [provided by RefSeq, Jul 2008]'