Human POU3F2 activation kit by CRISPRa

CAT#: GA103676

POU3F2 CRISPRa kit - CRISPR gene activation of human POU class 3 homeobox 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: POU3F2
• Locus ID: 5454
• Kit Components:

  GA103676G1, POU3F2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103676G2, POU3F2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103676G3, POU3F2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005604
• Synonyms: brn-2; BRN2; N-Oct3; oct-7; OCT7; OTF-7; OTF7; POUF3
• Summary: 'This gene encodes a member of the POU-III class of neural transcription factors. The encoded protein is involved in neuronal differentiation and enhances the activation of corticotropin-releasing hormone regulated genes. Overexpression of this protein is associated with an increase in the proliferation of melanoma cells. [provided by RefSeq, Mar 2012]'