Human PPP2R2A activation kit by CRISPRa

CAT#: GA103719

PPP2R2A CRISPRa kit - CRISPR gene activation of human protein phosphatase 2 regulatory subunit Balpha

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PPP2R2A
• Locus ID: 5520
• Kit Components:

  GA103719G1, PPP2R2A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103719G2, PPP2R2A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103719G3, PPP2R2A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001177591, NM_002717
• Synonyms: B55A; B55ALPHA; PR52A; PR55A
• Summary: 'The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B55 subfamily. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010]'