Human PPP2R5D activation kit by CRISPRa

CAT#: GA103727

PPP2R5D CRISPRa kit - CRISPR gene activation of human protein phosphatase 2 regulatory subunit B'delta

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PPP2R5D
• Locus ID: 5528
• Kit Components:

  GA103727G1, PPP2R5D gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103727G2, PPP2R5D gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103727G3, PPP2R5D gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001270476, NM_006245, NM_180976, NM_180977
• Synonyms: B56D; MRD35
• Summary: 'The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a delta isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]'