Human PROP1 activation kit by CRISPRa

CAT#: GA103812

PROP1 CRISPRa kit - CRISPR gene activation of human PROP paired-like homeobox 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PROP1
• Locus ID: 5626
• Kit Components:

  GA103812G1, PROP1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA103812G2, PROP1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA103812G3, PROP1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006261
• Synonyms: CPHD2; PROP-1
• Summary: This gene encodes a paired-like homeodomain transcription factor in the developing pituitary gland. Expression occurs prior to and is required for expression of pou domain transcription factor 1, which is responsible for pituitary development and hormone expression. Mutations in this gene have been associated with combined pituitary hormone deficiency-2 as well as deficiencies in luteinizing hormone, follicle-stimulating hormone, growth hormone, prolactin, and thyroid-stimulating hormone. [provided by RefSeq, Sep 2011]