Human Trypsin (PRSS3) activation kit by CRISPRa

CAT#: GA103826

PRSS3 CRISPRa kit - CRISPR gene activation of human serine protease 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PRSS3
• Locus ID: 5646
• Kit Components:

  GA103826G1, Trypsin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103826G2, Trypsin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103826G3, Trypsin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001197097, NM_001197098, NM_002771, NM_007343
• Synonyms: MTG; PRSS4; T9; TRY3; TRY4
• Summary: 'This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is expressed in the brain and pancreas and is resistant to common trypsin inhibitors. It is active on peptide linkages involving the carboxyl group of lysine or arginine. This gene is localized to the locus of T cell receptor beta variable orphans on chromosome 9. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2010]'