Human PSG6 activation kit by CRISPRa

CAT#: GA103846

PSG6 CRISPRa kit - CRISPR gene activation of human pregnancy specific beta-1-glycoprotein 6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PSG6
• Locus ID: 5675
• Kit Components:

  GA103846G1, PSG6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103846G2, PSG6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103846G3, PSG6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001031850, NM_002782
• Synonyms: PSBG-6; PSBG-10; PSBG-12; PSG10; PSGGB
• Summary: 'This gene is a member of the pregnancy-specific glycoprotein (PSG) gene family. The PSG genes are a subgroup of the carcinoembryonic antigen (CEA) family of immunoglobulin-like genes, and are found in a gene cluster at 19q13.1-q13.2 telomeric to another cluster of CEA-related genes. The PSG genes are expressed by placental trophoblasts and released into the maternal circulation during pregnancy, and are thought to be essential for maintenance of normal pregnancy. The protein encoded by this gene contains the Arg-Gly-Asp tripeptide associated with cellular adhesion and recognition. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012]'