Human Rad9 (RAD9A) activation kit by CRISPRa

CAT#: GA103996

RAD9A CRISPRa kit - CRISPR gene activation of human RAD9 checkpoint clamp component A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RAD9A
• Locus ID: 5883
• Kit Components:

  GA103996G1, Rad9 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103996G2, Rad9 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103996G3, Rad9 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001243224, NM_004584
• Synonyms: RAD9
• Summary: 'This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair. This protein possesses 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]'