Human RAG1 activation kit by CRISPRa

CAT#: GA104008

RAG1 CRISPRa kit - CRISPR gene activation of human recombination activating 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RAG1
• Locus ID: 5896
• Kit Components:

  GA104008G1, RAG1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104008G2, RAG1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104008G3, RAG1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000448
• Synonyms: RAG-1; RNF74
• Summary: 'The protein encoded by this gene is involved in activation of immunoglobulin V-D-J recombination. The encoded protein is involved in recognition of the DNA substrate, but stable binding and cleavage activity also requires RAG2. Defects in this gene can be the cause of several diseases. [provided by RefSeq, Jul 2008]'