Human Sodium Iodide Symporter (SLC5A5) activation kit by CRISPRa

CAT#: GA104452

SLC5A5 CRISPRa kit - CRISPR gene activation of human solute carrier family 5 member 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SLC5A5
• Locus ID: 6528
• Kit Components:

  GA104452G1, Sodium Iodide Symporter gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104452G2, Sodium Iodide Symporter gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104452G3, Sodium Iodide Symporter gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000453
• Synonyms: NIS; TDH1
• Summary: 'This gene encodes a member of the sodium glucose cotransporter family. The encoded protein is responsible for the uptake of iodine in tissues such as the thyroid and lactating breast tissue. The iodine taken up by the thyroid is incorporated into the metabolic regulators triiodothyronine (T3) and tetraiodothyronine (T4). Mutations in this gene are associated with thyroid dyshormonogenesis 1.[provided by RefSeq, Sep 2009]'