Human SLUG (SNAI2) activation kit by CRISPRa

CAT#: GA104507

SNAI2 CRISPRa kit - CRISPR gene activation of human snail family transcriptional repressor 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SNAI2
• Locus ID: 6591
• Kit Components:

  GA104507G1, SLUG gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104507G2, SLUG gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104507G3, SLUG gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003068
• Synonyms: SLUG; SLUGH1; SNAIL2; WS2D
• Summary: 'This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq, Jul 2008]'