Human SOX10 activation kit by CRISPRa

CAT#: GA104572

SOX10 CRISPRa kit - CRISPR gene activation of human SRY-box transcription factor 10

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SOX10
• Locus ID: 6663
• Kit Components:

  GA104572G1, SOX10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104572G2, SOX10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104572G3, SOX10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006941
• Synonyms: DOM; PCWH; WS2E; WS4; WS4C
• Summary: 'This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease. [provided by RefSeq, Jul 2008]'