Human SPINK1 activation kit by CRISPRa

CAT#: GA104590

SPINK1 CRISPRa kit - CRISPR gene activation of human serine peptidase inhibitor, Kazal type 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SPINK1
• Locus ID: 6690
• Kit Components:

  GA104590G1, SPINK1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104590G2, SPINK1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104590G3, SPINK1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003122, NM_001354966
• Synonyms: PCTT; PSTI; Spink3; TATI; TCP
• Summary: 'The protein encoded by this gene is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis. [provided by RefSeq, Oct 2008]'